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Parallel evaluation of cell-based phage display panning strategies: Optimized selection and depletion steps result in AML blast-binding consensus antibodies

Phage display technology (PD) is a powerful technique for the generation of tumor-targeting antibodies. However, there are a number of different selection methods established in different laboratories around the world. Cell-based PD panning methods using primary tumor cells are particularly heteroge...

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Detalles Bibliográficos
Autores principales: Weber, Theresa, Pscherer, Sibylle, Gamerdinger, Ulrike, Teigler-Schlegel, Andrea, Rutz, Natalja, Blau, Wolfgang, Rummel, Mathias, Gattenlöhner, Stefan, Tur, Mehmet Kemal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430305/
https://www.ncbi.nlm.nih.gov/pubmed/34490477
http://dx.doi.org/10.3892/mmr.2021.12407