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Salvianolic acid B improves autophagic dysfunction and decreases the apoptosis of cholesterol crystal-induced macrophages via inhibiting the Akt/mTOR signaling pathway

Progressive macrophage dysfunction and apoptosis are some of the major events that occur during atherogenesis. To further investigate the intrinsic association between atherosclerosis (AS) and macrophage apoptosis and autophagy, cholesterol crystals (CHCs) were used to stimulate RAW264.7 macrophages...

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Detalles Bibliográficos
Autores principales: Sun, Mengqi, Ye, Yun, Huang, Yilan, Yin, Wenxian, Yu, Zhaolan, Wang, Shurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430306/
https://www.ncbi.nlm.nih.gov/pubmed/34490483
http://dx.doi.org/10.3892/mmr.2021.12403