Cargando…
Salvianolic acid B improves autophagic dysfunction and decreases the apoptosis of cholesterol crystal-induced macrophages via inhibiting the Akt/mTOR signaling pathway
Progressive macrophage dysfunction and apoptosis are some of the major events that occur during atherogenesis. To further investigate the intrinsic association between atherosclerosis (AS) and macrophage apoptosis and autophagy, cholesterol crystals (CHCs) were used to stimulate RAW264.7 macrophages...
Autores principales: | Sun, Mengqi, Ye, Yun, Huang, Yilan, Yin, Wenxian, Yu, Zhaolan, Wang, Shurong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430306/ https://www.ncbi.nlm.nih.gov/pubmed/34490483 http://dx.doi.org/10.3892/mmr.2021.12403 |
Ejemplares similares
-
Salvianolic acid B inhibits RAW264.7 cell polarization towards the M1 phenotype by inhibiting NF-κB and Akt/mTOR pathway activation
por: Zou, Tao, et al.
Publicado: (2022) -
Crocin induces autophagic apoptosis in hepatocellular carcinoma by inhibiting Akt/mTOR activity
por: Yao, Chong, et al.
Publicado: (2018) -
Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway
por: Shi, Lungang, et al.
Publicado: (2019) -
Lomitapide, a cholesterol-lowering drug, is an anticancer agent that induces autophagic cell death via inhibiting mTOR
por: Lee, Boah, et al.
Publicado: (2022) -
Moxidectin induces Cytostatic Autophagic Cell Death of Glioma Cells through inhibiting the AKT/mTOR Signalling Pathway
por: Liu, Jingjing, et al.
Publicado: (2020)