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Stress Granules Modulate SYK to Cause Tau-Associated Neurocognitive Deterioration in 5XFAD Mouse After Anesthesia and Surgery

BACKGROUND: Alzheimer’s disease (AD) is the most common type of dementia. However, no curative therapy has been found effective to slow down the process of AD. It is reported that anesthesia and surgery will induce neurocognitive deterioration in AD, but the mechanism is not quite clear. In this stu...

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Detalles Bibliográficos
Autores principales: Shen, Yang, Zhang, Tong, Zhang, Yinglin, Wang, Yinuo, Yao, Junyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430336/
https://www.ncbi.nlm.nih.gov/pubmed/34512311
http://dx.doi.org/10.3389/fnagi.2021.718701