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Optimizing oxytocin LC-MS/MS sensitivity by choosing the right column

OBJECTIVE: Sensitivity is often an issue in bioanalytical LC-MS/MS applications. Commonly investigated parameters to improve it include additives to mobile phase, derivatization and sample-preparation. The nature of the column, however, is not frequently evaluated. DESIGN AND METHODS: The sensitivit...

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Detalles Bibliográficos
Autor principal: Ackermans, Mariëtte T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430380/
https://www.ncbi.nlm.nih.gov/pubmed/34527802
http://dx.doi.org/10.1016/j.plabm.2021.e00254