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Erasing m(6)A-dependent transcription signature of stress-sensitive genes triggers antidepressant actions

Emerging evidence has shown that stress responsivity and psychiatric diseases are associated with alterations in N(6)-methyladenosine (m(6)A) mRNA epigenetic modifications. Fat mass and obesity-associated protein (FTO) is an m(6)A demethylase that has been linked to increased body mass and obesity....

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Detalles Bibliográficos
Autores principales: Wu, Peng-Fei, Han, Qian-Qian, Chen, Fu-Feng, Shen, Tian-Tian, Li, Yi-Heng, Cao, Yu, Chen, Jian-Guo, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430387/
https://www.ncbi.nlm.nih.gov/pubmed/34527794
http://dx.doi.org/10.1016/j.ynstr.2021.100390