Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences

3,4-Methylenedioxymethamphetamine (MDMA, “ecstasy”) is an amphetamine-related drug that may damage the dopaminergic nigrostriatal system. To investigate the mechanisms that sustain this toxic effect and ascertain their sex-dependence, we evaluated in the nigrostriatal system of MDMA-treated (4 × 20 ...

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Detalles Bibliográficos
Autores principales: Costa, Giulia, Caputi, Francesca Felicia, Serra, Marcello, Simola, Nicola, Rullo, Laura, Stamatakos, Serena, Sanna, Fabrizio, Germain, Marc, Martinoli, Maria-Grazia, Candeletti, Sanzio, Morelli, Micaela, Romualdi, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430399/
https://www.ncbi.nlm.nih.gov/pubmed/34512343
http://dx.doi.org/10.3389/fphar.2021.713486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430399/
https://www.ncbi.nlm.nih.gov/pubmed/34512343
http://dx.doi.org/10.3389/fphar.2021.713486

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