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Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences
3,4-Methylenedioxymethamphetamine (MDMA, “ecstasy”) is an amphetamine-related drug that may damage the dopaminergic nigrostriatal system. To investigate the mechanisms that sustain this toxic effect and ascertain their sex-dependence, we evaluated in the nigrostriatal system of MDMA-treated (4 × 20 ...
Autores principales: | Costa, Giulia, Caputi, Francesca Felicia, Serra, Marcello, Simola, Nicola, Rullo, Laura, Stamatakos, Serena, Sanna, Fabrizio, Germain, Marc, Martinoli, Maria-Grazia, Candeletti, Sanzio, Morelli, Micaela, Romualdi, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430399/ https://www.ncbi.nlm.nih.gov/pubmed/34512343 http://dx.doi.org/10.3389/fphar.2021.713486 |
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