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Cost-effectiveness Analysis of Genotype-Specific Surveillance and Preventive Strategies for Gynecologic Cancers Among Women With Lynch Syndrome

IMPORTANCE: With the expansion of multigene testing for cancer susceptibility, Lynch syndrome (LS) has become more readily identified among women. The condition is caused by germline pathogenic variants in DNA mismatch repair genes (ie, MLH1, MSH2, MSH6, and PMS2) and is associated with high but var...

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Detalles Bibliográficos
Autores principales: Wright, Jason D., Silver, Elisabeth R., Tan, Sarah Xinhui, Hur, Chin, Kastrinos, Fay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430458/
https://www.ncbi.nlm.nih.gov/pubmed/34499134
http://dx.doi.org/10.1001/jamanetworkopen.2021.23616