New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway

Under metabolic stress conditions such as hypoxia and glucose deprivation, an increase in the AMP:ATP ratio activates the AMP-activated protein kinase (AMPK) pathway, resulting in the modulation of cellular metabolism. Metformin, which is widely prescribed for type 2 diabetes mellitus (T2DM) patient...

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Detalles Bibliográficos
Autores principales: Hsu, Sheng-Kai, Cheng, Kai-Chun, Mgbeahuruike, Miracle Oluebube, Lin, Yi-Hsiung, Wu, Chang-Yi, Wang, Hui-Min David, Yen, Chia-Hung, Chiu, Chien-Chih, Sheu, Shwu-Jiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430477/
https://www.ncbi.nlm.nih.gov/pubmed/34502359
http://dx.doi.org/10.3390/ijms22179453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430477/
https://www.ncbi.nlm.nih.gov/pubmed/34502359
http://dx.doi.org/10.3390/ijms22179453

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