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Effects of Metformin on Spontaneous Ca(2+) Signals in Cultured Microglia Cells under Normoxic and Hypoxic Conditions

Microglial functioning depends on Ca(2+) signaling. By using Ca(2+) sensitive fluorescence dye, we studied how inhibition of mitochondrial respiration changed spontaneous Ca(2+) signals in soma of microglial cells from 5–7-day-old rats grown under normoxic and mild-hypoxic conditions. In microglia u...

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Detalles Bibliográficos
Autores principales: Jankeviciute, Silvija, Svirskiene, Natasa, Svirskis, Gytis, Borutaite, Vilmante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430509/
https://www.ncbi.nlm.nih.gov/pubmed/34502402
http://dx.doi.org/10.3390/ijms22179493