Enhancement of Neuroblastoma NK-Cell-Mediated Lysis through NF-kB p65 Subunit-Induced Expression of FAS and PVR, the Loss of Which Is Associated with Poor Patient Outcome

SIMPLE SUMMARY: Neuroblastoma (NB) cells adopt several molecular strategies to evade the Natural Killer (NK)-mediated response. Herein, we found that the overexpression of the NF-kB p65 subunit in NB cell lines upregulates the expression of both the death receptor FAS and the activating ligand PVR,...

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Detalles Bibliográficos
Autores principales: Brandetti, Elisa, Focaccetti, Chiara, Pezzolo, Annalisa, Ognibene, Marzia, Folgiero, Valentina, Cotugno, Nicola, Benvenuto, Monica, Palma, Paolo, Manzari, Vittorio, Rossi, Paolo, Fruci, Doriana, Bei, Roberto, Cifaldi, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430542/
https://www.ncbi.nlm.nih.gov/pubmed/34503178
http://dx.doi.org/10.3390/cancers13174368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430542/
https://www.ncbi.nlm.nih.gov/pubmed/34503178
http://dx.doi.org/10.3390/cancers13174368

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