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Enhancement of Neuroblastoma NK-Cell-Mediated Lysis through NF-kB p65 Subunit-Induced Expression of FAS and PVR, the Loss of Which Is Associated with Poor Patient Outcome
SIMPLE SUMMARY: Neuroblastoma (NB) cells adopt several molecular strategies to evade the Natural Killer (NK)-mediated response. Herein, we found that the overexpression of the NF-kB p65 subunit in NB cell lines upregulates the expression of both the death receptor FAS and the activating ligand PVR,...
Autores principales: | Brandetti, Elisa, Focaccetti, Chiara, Pezzolo, Annalisa, Ognibene, Marzia, Folgiero, Valentina, Cotugno, Nicola, Benvenuto, Monica, Palma, Paolo, Manzari, Vittorio, Rossi, Paolo, Fruci, Doriana, Bei, Roberto, Cifaldi, Loredana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430542/ https://www.ncbi.nlm.nih.gov/pubmed/34503178 http://dx.doi.org/10.3390/cancers13174368 |
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