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Anti-TRBC1 Antibody-Based Flow Cytometric Detection of T-Cell Clonality: Standardization of Sample Preparation and Diagnostic Implementation

SIMPLE SUMMARY: The anti-TRBC1 antibody JOVI-1 has recently been identified as a flow cytometry marker potentially useful for assessment of T-cell clonality. The aim of this study was to optimize a flow cytometric method for routine use of anti-TRBC1 to assess T-cell clonality and validate it in a l...

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Detalles Bibliográficos
Autores principales: Muñoz-García, Noemí, Lima, Margarida, Villamor, Neus, Morán-Plata, F. Javier, Barrena, Susana, Mateos, Sheila, Caldas, Carolina, Balanzategui, Ana, Alcoceba, Miguel, Domínguez, Alejandro, Gómez, Fabio, Langerak, Anton W., van Dongen, Jacques J. M., Orfao, Alberto, Almeida, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430560/
https://www.ncbi.nlm.nih.gov/pubmed/34503189
http://dx.doi.org/10.3390/cancers13174379