Enhancer of Zeste Homolog 2 (EZH2) Contributes to Rod Photoreceptor Death Process in Several Forms of Retinal Degeneration and Its Activity Can Serve as a Biomarker for Therapy Efficacy

Inherited retinal dystrophies (IRD) are due to various gene mutations. Each mutated gene instigates a specific cell homeostasis disruption, leading to a modification in gene expression and retinal degeneration. We previously demonstrated that the polycomb-repressive complex-1 (PRC1) markedly contrib...

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Detalles Bibliográficos
Autores principales: Mbefo, Martial, Berger, Adeline, Schouwey, Karine, Gérard, Xavier, Kostic, Corinne, Beryozkin, Avigail, Sharon, Dror, Dolfuss, Hélène, Munier, Francis, Tran, Hoai Viet, van Lohuizen, Maarten, Beltran, William A., Arsenijevic, Yvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430630/
https://www.ncbi.nlm.nih.gov/pubmed/34502238
http://dx.doi.org/10.3390/ijms22179331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430630/
https://www.ncbi.nlm.nih.gov/pubmed/34502238
http://dx.doi.org/10.3390/ijms22179331

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