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The Extracellular Matrix in Pancreatic Cancer: Description of a Complex Network and Promising Therapeutic Options

SIMPLE SUMMARY: This review depicts the principal mechanisms involved in the process of stromal desmoplasia characterizing pancreatic ductal adenocarcinoma (PDAC). The aim of this review is to point out the role of the dense extracellular matrix in worsening PDAC responsiveness to conventional thera...

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Detalles Bibliográficos
Autores principales: Ferrara, Benedetta, Pignatelli, Cataldo, Cossutta, Mélissande, Citro, Antonio, Courty, José, Piemonti, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430646/
https://www.ncbi.nlm.nih.gov/pubmed/34503252
http://dx.doi.org/10.3390/cancers13174442