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The Unfolded Protein Response Is Associated with Cancer Proliferation and Worse Survival in Hepatocellular Carcinoma

SIMPLE SUMMARY: We studied the association between the unfolded protein response (UPR) and carcinogenesis, cancer progression, and survival in hepatocellular carcinoma (HCC). We studied 655 HCC patients from 4 independent cohorts using an UPR score. The UPR was enhanced as normal liver became cancer...

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Detalles Bibliográficos
Autores principales: Patel, Ankit, Oshi, Masanori, Yan, Li, Matsuyama, Ryusei, Endo, Itaru, Takabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430652/
https://www.ncbi.nlm.nih.gov/pubmed/34503253
http://dx.doi.org/10.3390/cancers13174443