Cyclopentanone Derivative Attenuates Memory Impairment by Inhibiting Amyloid Plaques Formation in the 5xFAD Mice

Alzheimer’s disease (AD) is a chronic neurodegenerative disorder. This study was designed to investigate the effects of cyclopentanone derivative i.e., 2-(hydroxyl-(3-nitrophenyl)methyl)cyclopentanone (3NCP) on behavior, amyloid β (Aβ) plaque deposition, and βAPP cleaving enzyme-1 (BACE-1) expressio...

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Detalles Bibliográficos
Autores principales: Ullah, Rahim, Ali, Gowhar, Khan, Ajmal, Ahmad, Sajjad, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430684/
https://www.ncbi.nlm.nih.gov/pubmed/34502467
http://dx.doi.org/10.3390/ijms22179559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430684/
https://www.ncbi.nlm.nih.gov/pubmed/34502467
http://dx.doi.org/10.3390/ijms22179559

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