Quantitative Analysis of the Potency of Equimolar Two-Drug Combinations and Combi-Molecules Involving Kinase Inhibitors In Vitro: The Concept of Balanced Targeting

The median-effect principle proposed by Chou and Talalay is the most effective approach to parameterize interactions between several agents in combination. However, this method cannot be used to evaluate the effectiveness of equimolar drug combinations, which are comparative references for dual-targ...

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Detalles Bibliográficos
Autores principales: Rao, Suman, Thibault, Benoît, Peyrard, Lisa, Larroque-Lombard, Anne-Laure, Rupp, Martin, Thauvin, Cédric, Jean-Claude, Bertrand J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430702/
https://www.ncbi.nlm.nih.gov/pubmed/34502481
http://dx.doi.org/10.3390/ijms22179569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430702/
https://www.ncbi.nlm.nih.gov/pubmed/34502481
http://dx.doi.org/10.3390/ijms22179569

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