Metastatic Melanoma Progression Is Associated with Endothelial Nitric Oxide Synthase Uncoupling Induced by Loss of eNOS:BH4 Stoichiometry

Melanoma is the most aggressive type of skin cancer due to its high capability of developing metastasis and acquiring chemoresistance. Altered redox homeostasis induced by increased reactive oxygen species is associated with melanomagenesis through modulation of redox signaling pathways. Dysfunction...

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Detalles Bibliográficos
Autores principales: de Melo, Fabiana Henriques Machado, Gonçalves, Diego Assis, de Sousa, Ricardo Xisto, Icimoto, Marcelo Yudi, Fernandes, Denise de Castro, Laurindo, Francisco R. M., Jasiulionis, Miriam Galvonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430733/
https://www.ncbi.nlm.nih.gov/pubmed/34502464
http://dx.doi.org/10.3390/ijms22179556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430733/
https://www.ncbi.nlm.nih.gov/pubmed/34502464
http://dx.doi.org/10.3390/ijms22179556

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