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Alisporivir Treatment Alleviates Mitochondrial Dysfunction in the Skeletal Muscles of C57BL/6NCrl Mice with High-Fat Diet/Streptozotocin-Induced Diabetes Mellitus

Diabetes mellitus is a systemic metabolic disorder associated with mitochondrial dysfunction, with mitochondrial permeability transition (MPT) pore opening being recognized as one of its pathogenic mechanisms. Alisporivir has been recently identified as a non-immunosuppressive analogue of the MPT po...

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Detalles Bibliográficos
Autores principales: Belosludtsev, Konstantin N., Starinets, Vlada S., Talanov, Eugeny Yu., Mikheeva, Irina B., Dubinin, Mikhail V., Belosludtseva, Natalia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430760/
https://www.ncbi.nlm.nih.gov/pubmed/34502433
http://dx.doi.org/10.3390/ijms22179524