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Trans-Chalcone Plus Baicalein Synergistically Reduce Intracellular Amyloid Beta (Aβ(42)) and Protect from Aβ(42) Induced Oxidative Damage in Yeast Models of Alzheimer’s Disease

Finding an effective therapeutic to prevent or cure AD has been difficult due to the complexity of the brain and limited experimental models. This study utilized unmodified and genetically modified Saccharomyces cerevisiae as model organisms to find potential natural bioactive compounds capable of r...

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Detalles Bibliográficos
Autores principales: Dhakal, Sudip, Ramsland, Paul A., Adhikari, Benu, Macreadie, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430801/
https://www.ncbi.nlm.nih.gov/pubmed/34502362
http://dx.doi.org/10.3390/ijms22179456