Overview of Ferroptosis and Synthetic Lethality Strategies

Ferroptosis, a term first proposed in 2012, is iron-dependent, non-apoptotic regulatory cell death induced by erastin. Ferroptosis was originally discovered during synthetic lethal screening for drugs sensitive to RAS mutant cells, and is closely related to synthetic lethality. Ferroptosis sensitize...

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Detalles Bibliográficos
Autores principales: Kinowaki, Yuko, Taguchi, Towako, Onishi, Iichiroh, Kirimura, Susumu, Kitagawa, Masanobu, Yamamoto, Kouhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430824/
https://www.ncbi.nlm.nih.gov/pubmed/34502181
http://dx.doi.org/10.3390/ijms22179271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430824/
https://www.ncbi.nlm.nih.gov/pubmed/34502181
http://dx.doi.org/10.3390/ijms22179271

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