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p53 Activation in Genetic Disorders: Different Routes to the Same Destination

The tumor suppressor p53 is critical for preventing neoplastic transformation and tumor progression. Inappropriate activation of p53, however, has been observed in a number of human inherited disorders that most often affect development of the brain, craniofacial region, limb skeleton, and hematopoi...

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Detalles Bibliográficos
Autores principales: Tsai, Yu-Young, Su, Chun-Hao, Tarn, Woan-Yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430931/
https://www.ncbi.nlm.nih.gov/pubmed/34502215
http://dx.doi.org/10.3390/ijms22179307