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S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P(1) and S1P(3) Receptor Activation and HIF-2α Stabilization

Erythropoietin (Epo) is the critical hormone for erythropoiesis. In adults, Epo is mainly produced by a subset of interstitial fibroblasts in the kidney, with minor amounts being produced in the liver and the brain. In this study, we used the immortalized renal interstitial fibroblast cell line FAIK...

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Detalles Bibliográficos
Autores principales: Hafizi, Redona, Imeri, Faik, Wenger, Roland H., Huwiler, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430949/
https://www.ncbi.nlm.nih.gov/pubmed/34502385
http://dx.doi.org/10.3390/ijms22179467