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DHX30 Coordinates Cytoplasmic Translation and Mitochondrial Function Contributing to Cancer Cell Survival

SIMPLE SUMMARY: Translation occurs in the cell both through cytoplasmic and mitochondrial ribosomes, respectively translating mRNAs encoded by the nuclear and the mitochondrial genome. Here we found that the silencing of DHX30, an RNA-binding protein that we previously studied for its role in p53-de...

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Detalles Bibliográficos
Autores principales: Bosco, Bartolomeo, Rossi, Annalisa, Rizzotto, Dario, Hamadou, Meriem Hadjer, Bisio, Alessandra, Giorgetta, Sebastiano, Perzolli, Alicia, Bonollo, Francesco, Gaucherot, Angeline, Catez, Frédéric, Diaz, Jean-Jacques, Dassi, Erik, Inga, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430983/
https://www.ncbi.nlm.nih.gov/pubmed/34503222
http://dx.doi.org/10.3390/cancers13174412