Niraparib Suppresses Cholangiocarcinoma Tumor Growth by Inducing Oxidative and Replication Stress

SIMPLE SUMMARY: Cholangiocarcinoma (CCA) is a rare and highly aggressive tumor with limited therapeutic options, thus underscoring the need to develop novel therapeutic approaches. We analyzed a publicly available CCA patient database to identify mutations in DNA damage response (DDR) genes. Mutatio...

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Detalles Bibliográficos
Autores principales: Bezrookove, Vladimir, Patino, John M., Nosrati, Mehdi, Desprez, Pierre-Yves, McAllister, Sean, Soroceanu, Liliana, Baron, Ari, Osorio, Robert, Kashani-Sabet, Mohammed, Dar, Altaf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430987/
https://www.ncbi.nlm.nih.gov/pubmed/34503215
http://dx.doi.org/10.3390/cancers13174405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430987/
https://www.ncbi.nlm.nih.gov/pubmed/34503215
http://dx.doi.org/10.3390/cancers13174405

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