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Phenotypic Characterization of Immortalized Chondrocytes from a Desbuquois Dysplasia Type 1 Mouse Model: A Tool for Studying Defects in Glycosaminoglycan Biosynthesis

The complexity of skeletal pathologies makes use of in vivo models essential to elucidate the pathogenesis of the diseases; nevertheless, chondrocyte and osteoblast cell lines provide relevant information on the underlying disease mechanisms. Due to the limitations of primary chondrocytes, immortali...

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Detalles Bibliográficos
Autores principales: Gramegna Tota, Chiara, Valenti, Beatrice, Forlino, Antonella, Rossi, Antonio, Paganini, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431031/
https://www.ncbi.nlm.nih.gov/pubmed/34502207
http://dx.doi.org/10.3390/ijms22179304