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Comprehensively Exploring the Mutational Landscape and Patterns of Genomic Evolution in Hypermutated Cancers

SIMPLE SUMMARY: To identify potential genetic markers for evaluating hypermutated cancers, we investigated driver mutations, mutational signatures, tumor-associated neoantigens, and molecular cancer evolution in the genetic variants of 533 cancer patients with six different cancer types. Driver muta...

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Detalles Bibliográficos
Autores principales: Lin, Peng-Chan, Yeh, Yu-Min, Hsu, Hui-Ping, Chan, Ren-Hao, Lin, Bo-Wen, Chen, Po-Chuan, Pan, Chien-Chang, Hsu, Keng-Fu, Hsiao, Jenn-Ren, Shan, Yan-Shen, Shen, Meng-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431047/
https://www.ncbi.nlm.nih.gov/pubmed/34503126
http://dx.doi.org/10.3390/cancers13174317