Protective Role of a Donepezil-Huprine Hybrid against the β-Amyloid (1-42) Effect on Human Erythrocytes

Aβ(1-42) peptide is a neurotoxic agent strongly associated with the etiology of Alzheimer’s disease (AD). Current treatments are still of very low effectiveness, and deaths from AD are increasing worldwide. Huprine-derived molecules have a high affinity towards the enzyme acetylcholinesterase (AChE)...

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Detalles Bibliográficos
Autores principales: Zambrano, Pablo, Suwalsky, Mario, Jemiola-Rzeminska, Malgorzata, Gallardo-Nelson, María José, Strzalka, Kazimierz, Muñoz-Torrero, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431064/
https://www.ncbi.nlm.nih.gov/pubmed/34502472
http://dx.doi.org/10.3390/ijms22179563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431064/
https://www.ncbi.nlm.nih.gov/pubmed/34502472
http://dx.doi.org/10.3390/ijms22179563

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