Cardiac Extracellular Matrix Hydrogel Enriched with Polyethylene Glycol Presents Improved Gelation Time and Increased On-Target Site Retention of Extracellular Vesicles

Stem-cell-derived extracellular vesicles (EVs) have demonstrated multiple beneficial effects in preclinical models of cardiac diseases. However, poor retention at the target site may limit their therapeutic efficacy. Cardiac extracellular matrix hydrogels (cECMH) seem promising as drug-delivery mate...

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Detalles Bibliográficos
Autores principales: Gómez-Cid, Lidia, López-Donaire, María Luisa, Velasco, Diego, Marín, Víctor, González, María Isabel, Salinas, Beatriz, Cussó, Lorena, García, Ángel, Bravo, Susana Belén, Fernández-Santos, María Eugenia, Elvira, Carlos, Sierra, Johanna, Arroba, Ester, Bañares, Rafael, Grigorian-Shamagian, Lilian, Fernández-Avilés, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431142/
https://www.ncbi.nlm.nih.gov/pubmed/34502146
http://dx.doi.org/10.3390/ijms22179226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431142/
https://www.ncbi.nlm.nih.gov/pubmed/34502146
http://dx.doi.org/10.3390/ijms22179226

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