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Cardiac Extracellular Matrix Hydrogel Enriched with Polyethylene Glycol Presents Improved Gelation Time and Increased On-Target Site Retention of Extracellular Vesicles
Stem-cell-derived extracellular vesicles (EVs) have demonstrated multiple beneficial effects in preclinical models of cardiac diseases. However, poor retention at the target site may limit their therapeutic efficacy. Cardiac extracellular matrix hydrogels (cECMH) seem promising as drug-delivery mate...
Autores principales: | Gómez-Cid, Lidia, López-Donaire, María Luisa, Velasco, Diego, Marín, Víctor, González, María Isabel, Salinas, Beatriz, Cussó, Lorena, García, Ángel, Bravo, Susana Belén, Fernández-Santos, María Eugenia, Elvira, Carlos, Sierra, Johanna, Arroba, Ester, Bañares, Rafael, Grigorian-Shamagian, Lilian, Fernández-Avilés, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431142/ https://www.ncbi.nlm.nih.gov/pubmed/34502146 http://dx.doi.org/10.3390/ijms22179226 |
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