Dual Activity BLEG-1 from Bacillus lehensis G1 Revealed Structural Resemblance to B3 Metallo-β-Lactamase and Glyoxalase II: An Insight into Its Enzyme Promiscuity and Evolutionary Divergence

Metallo-β-lactamases (MBLs) are class B β-lactamases from the metallo-hydrolase-like MBL-fold superfamily which act on a broad range of β-lactam antibiotics. A previous study on BLEG-1 (formerly called Bleg1_2437), a hypothetical protein from Bacillus lehensis G1, revealed sequence similarity and ac...

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Detalles Bibliográficos
Autores principales: Au, Shaw Xian, Dzulkifly, Nur Syazana, Muhd Noor, Noor Dina, Matsumura, Hiroyoshi, Raja Abdul Rahman, Raja Noor Zaliha, Normi, Yahaya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431146/
https://www.ncbi.nlm.nih.gov/pubmed/34502284
http://dx.doi.org/10.3390/ijms22179377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431146/
https://www.ncbi.nlm.nih.gov/pubmed/34502284
http://dx.doi.org/10.3390/ijms22179377

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