Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus

The two-pore domain K(+) (K(2P)) channel, which is involved in setting the resting membrane potential in neurons, is an essential target for receptor agonists. Activation of the γ-aminobutyric acid (GABA) receptors (GABA(A)R and GABA(B)R) reduces cellular excitability through Cl(-) influx and K(+) e...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Jin, Kwon, Oh-Sang, Hur, Chang-Gi, Nyiramana, Marie Merci, Lee, Dong-Kun, Hong, Seong-Geun, Han, Jaehee, Kang, Dawon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431218/
https://www.ncbi.nlm.nih.gov/pubmed/34502229
http://dx.doi.org/10.3390/ijms22179320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431218/
https://www.ncbi.nlm.nih.gov/pubmed/34502229
http://dx.doi.org/10.3390/ijms22179320

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