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Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus
The two-pore domain K(+) (K(2P)) channel, which is involved in setting the resting membrane potential in neurons, is an essential target for receptor agonists. Activation of the γ-aminobutyric acid (GABA) receptors (GABA(A)R and GABA(B)R) reduces cellular excitability through Cl(-) influx and K(+) e...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431218/ https://www.ncbi.nlm.nih.gov/pubmed/34502229 http://dx.doi.org/10.3390/ijms22179320 |