The Antihypertensive Drug Telmisartan Protects Oligodendrocytes from Cholesterol Accumulation and Promotes Differentiation by a PPAR-γ-Mediated Mechanism

Our previous studies have demonstrated that specific peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists play a fundamental role in oligodendrocyte progenitor (OP) differentiation, protecting them against oxidative and inflammatory damage. The antihypertensive drug Telmisartan (TLM) was s...

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Detalles Bibliográficos
Autores principales: Bernardo, Antonietta, Malara, Mariagiovanna, Bertuccini, Lucia, De Nuccio, Chiara, Visentin, Sergio, Minghetti, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431237/
https://www.ncbi.nlm.nih.gov/pubmed/34502342
http://dx.doi.org/10.3390/ijms22179434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431237/
https://www.ncbi.nlm.nih.gov/pubmed/34502342
http://dx.doi.org/10.3390/ijms22179434

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