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The Antihypertensive Drug Telmisartan Protects Oligodendrocytes from Cholesterol Accumulation and Promotes Differentiation by a PPAR-γ-Mediated Mechanism
Our previous studies have demonstrated that specific peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists play a fundamental role in oligodendrocyte progenitor (OP) differentiation, protecting them against oxidative and inflammatory damage. The antihypertensive drug Telmisartan (TLM) was s...
Autores principales: | Bernardo, Antonietta, Malara, Mariagiovanna, Bertuccini, Lucia, De Nuccio, Chiara, Visentin, Sergio, Minghetti, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431237/ https://www.ncbi.nlm.nih.gov/pubmed/34502342 http://dx.doi.org/10.3390/ijms22179434 |
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