A Dansyl-Modified Sphingosine Kinase Inhibitor DPF-543 Enhanced De Novo Ceramide Generation

Sphingosine-1-phosphate (S1P) synthesized by sphingosine kinase (SPHK) is a signaling molecule, involved in cell proliferation, growth, differentiation, and survival. Indeed, a sharp increase of S1P is linked to a pathological outcome with inflammation, cancer metastasis, or angiogenesis, etc. In th...

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Detalles Bibliográficos
Autores principales: Shamshiddinova, Maftuna, Gulyamov, Shokhid, Kim, Hee-Jung, Jung, Seo-Hyeon, Baek, Dong-Jae, Lee, Yong-Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431253/
https://www.ncbi.nlm.nih.gov/pubmed/34502095
http://dx.doi.org/10.3390/ijms22179190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431253/
https://www.ncbi.nlm.nih.gov/pubmed/34502095
http://dx.doi.org/10.3390/ijms22179190

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