Zebrafish as a Model to Evaluate a CRISPR/Cas9-Based Exon Excision Approach as a Future Treatment Option for EYS-Associated Retinitis Pigmentosa

Retinitis pigmentosa (RP) is an inherited retinal disease (IRD) with an overall prevalence of 1 in 4000 individuals. Mutations in EYS (Eyes shut homolog) are among the most frequent causes of non-syndromic autosomal recessively inherited RP and act via a loss-of-function mechanism. In light of the r...

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Detalles Bibliográficos
Autores principales: Schellens, Renske, de Vrieze, Erik, Graave, Pam, Broekman, Sanne, Nagel-Wolfrum, Kerstin, Peters, Theo, Kremer, Hannie, Collin, Rob W. J., van Wijk, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431288/
https://www.ncbi.nlm.nih.gov/pubmed/34502064
http://dx.doi.org/10.3390/ijms22179154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431288/
https://www.ncbi.nlm.nih.gov/pubmed/34502064
http://dx.doi.org/10.3390/ijms22179154

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