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Deregulated Expression of Immune Checkpoints on Circulating CD4 T Cells May Complicate Clinical Outcome and Response to Treatment with Checkpoint Inhibitors in Multiple Myeloma Patients

Unlike solid-tumor patients, a disappointingly small subset of multiple myeloma (MM) patients treated with checkpoint inhibitors derive clinical benefits, suggesting differential participation of inhibitory receptors involved in the development of T-cell-mediated immunosuppression. In fact, T cells...

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Detalles Bibliográficos
Autores principales: Kulikowska de Nałęcz, Anna, Ciszak, Lidia, Usnarska-Zubkiewicz, Lidia, Frydecka, Irena, Pawlak, Edyta, Szmyrka, Magdalena, Kosmaczewska, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431347/
https://www.ncbi.nlm.nih.gov/pubmed/34502204
http://dx.doi.org/10.3390/ijms22179298