The Second-Generation PIM Kinase Inhibitor TP-3654 Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs

Human ATP-binding cassette (ABC) subfamily G member 2 (ABCG2) mediates the transport of a wide variety of conventional cytotoxic anticancer drugs and molecular targeted agents. Consequently, the overexpression of ABCG2 in cancer cells is linked to the development of the multidrug resistance (MDR) ph...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Pu, Li, Yan-Qing, Chi, Ya-Chen, Huang, Yang-Hui, Hung, Tai-Ho, Wu, Yu-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431370/
https://www.ncbi.nlm.nih.gov/pubmed/34502348
http://dx.doi.org/10.3390/ijms22179440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431370/
https://www.ncbi.nlm.nih.gov/pubmed/34502348
http://dx.doi.org/10.3390/ijms22179440

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