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Fibrotic Changes to Schlemm’s Canal Endothelial Cells in Glaucoma

Previous studies have shown that glaucomatous Schlemm’s canal endothelial cells (gSCECs) are stiffer and associated with reduced porosity and increased extracellular matrix (ECM) material compared to SCECs from healthy individuals. We hypothesised that Schlemm’s canal (SC) cell stiffening was a func...

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Detalles Bibliográficos
Autores principales: Kelly, Ruth A., Perkumas, Kristin M., Campbell, Matthew, Farrar, G. Jane, Stamer, W. Daniel, Humphries, Pete, O’Callaghan, Jeffrey, O’Brien, Colm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431431/
https://www.ncbi.nlm.nih.gov/pubmed/34502356
http://dx.doi.org/10.3390/ijms22179446