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Light-Inducible Spatio-Temporal Control of TLR4 and NF-κB-Gluc Reporter in Human Pancreatic Cell Line

Augmented Toll-like receptor 4 (TLR4) expression was found in nearly 70% of patients with pancreatic adenocarcinoma, which is correlated with increased tumorigenesis and progression. In this study, we engineered a new light-oxygen-voltage-sensing (LOV) domain-based optogenetic cell line (opto-TLR4 P...

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Detalles Bibliográficos
Autores principales: Stierschneider, Anna, Grünstäudl, Petra, Colleselli, Katrin, Atzler, Josef, Klein, Christian T., Hundsberger, Harald, Wiesner, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431472/
https://www.ncbi.nlm.nih.gov/pubmed/34502140
http://dx.doi.org/10.3390/ijms22179232