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Light-Inducible Spatio-Temporal Control of TLR4 and NF-κB-Gluc Reporter in Human Pancreatic Cell Line
Augmented Toll-like receptor 4 (TLR4) expression was found in nearly 70% of patients with pancreatic adenocarcinoma, which is correlated with increased tumorigenesis and progression. In this study, we engineered a new light-oxygen-voltage-sensing (LOV) domain-based optogenetic cell line (opto-TLR4 P...
Autores principales: | Stierschneider, Anna, Grünstäudl, Petra, Colleselli, Katrin, Atzler, Josef, Klein, Christian T., Hundsberger, Harald, Wiesner, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431472/ https://www.ncbi.nlm.nih.gov/pubmed/34502140 http://dx.doi.org/10.3390/ijms22179232 |
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