Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation

A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been identified as the pathogen responsible for the outbreak of a severe, rapidly developing pneumonia (Coronavirus disease 2019, COVID-19). The virus enzyme, called 3CLpro or main protease (M(pro)), is essential...

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Detalles Bibliográficos
Autores principales: Di Micco, Simone, Musella, Simona, Sala, Marina, Scala, Maria C., Andrei, Graciela, Snoeck, Robert, Bifulco, Giuseppe, Campiglia, Pietro, Fasano, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431481/
https://www.ncbi.nlm.nih.gov/pubmed/34502335
http://dx.doi.org/10.3390/ijms22179427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431481/
https://www.ncbi.nlm.nih.gov/pubmed/34502335
http://dx.doi.org/10.3390/ijms22179427

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