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Design and Characterization of a Cell-Penetrating Peptide Derived from the SOX2 Transcription Factor

SOX2 is an oncogenic transcription factor overexpressed in nearly half of the basal-like triple-negative breast cancers associated with very poor outcomes. Targeting and inhibiting SOX2 is clinically relevant as high SOX2 mRNA levels are positively correlated with decreased overall survival and prog...

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Detalles Bibliográficos
Autores principales: Gandhi, Neha S., Wang, Edina, Sorolla, Anabel, Kan, Yu Jie, Malik, Adil, Batra, Jyotsna, Young, Kimberly A., Tie, Wan Jun, Blancafort, Pilar, Mancera, Ricardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431565/
https://www.ncbi.nlm.nih.gov/pubmed/34502261
http://dx.doi.org/10.3390/ijms22179354