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Design and Characterization of a Cell-Penetrating Peptide Derived from the SOX2 Transcription Factor
SOX2 is an oncogenic transcription factor overexpressed in nearly half of the basal-like triple-negative breast cancers associated with very poor outcomes. Targeting and inhibiting SOX2 is clinically relevant as high SOX2 mRNA levels are positively correlated with decreased overall survival and prog...
Autores principales: | Gandhi, Neha S., Wang, Edina, Sorolla, Anabel, Kan, Yu Jie, Malik, Adil, Batra, Jyotsna, Young, Kimberly A., Tie, Wan Jun, Blancafort, Pilar, Mancera, Ricardo L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431565/ https://www.ncbi.nlm.nih.gov/pubmed/34502261 http://dx.doi.org/10.3390/ijms22179354 |
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