Combination Therapy with STAT3 Inhibitor Enhances SERCA2a-Induced BMPR2 Expression and Inhibits Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a devastating lung disease characterized by the progressive obstruction of the distal pulmonary arteries (PA). Structural and functional alteration of pulmonary artery smooth muscle cells (PASMC) and endothelial cells (PAEC) contributes to PA wall remodeling...

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Detalles Bibliográficos
Autores principales: Bisserier, Malik, Katz, Michael G., Bueno-Beti, Carlos, Brojakowska, Agnieszka, Zhang, Shihong, Gubara, Sarah, Kohlbrenner, Erik, Fazal, Shahood, Fargnoli, Anthony, Dorfmuller, Peter, Humbert, Marc, Hata, Akiko, Goukassian, David A., Sassi, Yassine, Hadri, Lahouaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431626/
https://www.ncbi.nlm.nih.gov/pubmed/34502015
http://dx.doi.org/10.3390/ijms22179105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431626/
https://www.ncbi.nlm.nih.gov/pubmed/34502015
http://dx.doi.org/10.3390/ijms22179105

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