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Nicotine Neurotoxicity Involves Low Wnt1 Signaling in Spinal Locomotor Networks of the Postnatal Rodent Spinal Cord

The postnatal rodent spinal cord in-vitro is a useful model to investigate early pathophysiological changes after injury. While low dose nicotine (1 µM) induces neuroprotection, how higher doses affect spinal networks is unknown. Using spinal preparations of postnatal wild-type Wistar rat and Wnt1Cr...

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Detalles Bibliográficos
Autores principales: Kaur, Jaspreet, Mazzone, Graciela L., Aquino, Jorge B., Nistri, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431663/
https://www.ncbi.nlm.nih.gov/pubmed/34502498
http://dx.doi.org/10.3390/ijms22179572