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Measuring and Interpreting Nuclear Transport in Neurodegenerative Disease—The Example of C9orf72 ALS

Transport from and into the nucleus is essential to all eukaryotic life and occurs through the nuclear pore complex (NPC). There are a multitude of data supporting a role for nuclear transport in neurodegenerative diseases, but actual transport assays in disease models have provided diverse outcomes...

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Detalles Bibliográficos
Autores principales: Semmelink, Marije F. W., Steen, Anton, Veenhoff, Liesbeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431710/
https://www.ncbi.nlm.nih.gov/pubmed/34502125
http://dx.doi.org/10.3390/ijms22179217